Objective: To evaluate and compare the efficacy and safety of domestic cefuroxime and Zinacef. 目的比较国产注射用头孢呋辛钠与进口注射用头孢呋辛钠(对照组)治疗下呼吸道感染的疗效和安全性。
Methods: 40 patients were recruited and divided into 2 group by random and mono blind methods, and treated with Cefuroxime sodium and Zinacef respectively. 方法:急性细菌感染性疾病患者40例,进行前瞻性多中心随机单盲平行对照试验,分别给予国产与进口头孢呋辛钠治疗。
CONCLUSIONS Cefuroxime sodium injection can effectively treat lower respiratory infection and urinary tract infection caused by sensitive pathogenic bacteria, and furthermore, the occurrence rate of side-effect is low, which similar to the import product Zinacef. 结论注射用头孢呋辛钠对临床常见的致病菌引起的下呼吸道感染、泌尿系感染,临床疗效较好且不良反应发生率低,与进口西力欣相近。