Increased membrane fluidity resulted from the addition of antimycin A was also observed. 抗霉素A亦可使内膜的流动性增加。
Antimycin A has anti-apoptosis. 抗霉素A具有促凋亡作用。
An activity component was isolated from the culture of Streptomyces sp. by solvent extraction and column chromatography, and it was identified as antimycin A2 by structure elucidation. 从稀有放线菌7310菌株(Streptomycessp.)的发酵菌丝中经溶媒萃取和硅胶柱层析初步分离出来一种活性成分,经结构鉴定为抑菌霉素(antimycins)的A2组份。
Study on Pesticidal and Fungicidal Activity of Antimycin A2 抑菌霉素A2的抑菌和杀虫活性研究
Four antimycin components were isolated and purified from the fermentation broth by the combination of silica gel chromatography and high speed countercurrent chromatography ( HSCCC) methods. 此外实验建立了硅胶层析与高速逆流色谱相结合的现代分离纯化方法,对抗霉素的发酵液进行了分离纯化,并成功的从中分离出四个抗霉素的单一组分。
All these results indicated that Antimycin A inhibited calcium currents via H2O2-hydroxyl radicals/ cPKC ( mainly PKC βⅰ) pathway. 以上这些结果提示AntimycinA是通过H2O2-羟自由基-cPKC通路(主要是PKCβI)来发挥对于钙电流的抑制作用的。