Intrathecal delivery of these baclofen or morphine may be necessary. 鞘内提供这些巴氯酚或***可能是必要的。
Effect of intrathecal injection of morphine and baclofen on contents of spinal excitatory amino acids in rat model of incisional pain 鞘内注射***联合巴氯芬对切口痛大鼠脊髓兴奋性氨基酸含量的影响
Intrathecal baclofen was shown to be superior to placebo in the change from baseline in the Ashworth rating of spasticity and the frequency of spasms. 鞘内注射巴氯芬被证明是优于从基线的痉挛阿什沃思等级和频率变化的痉挛安慰剂。
Effects of repeated injection of GABA_B receptor agonist baclofen on mean blood pressure in rats GABAB受体激动剂巴氯酚重复注射对大鼠血压的影响
Inhibitory Effects of Baclofen on Isoguvacine-and Muscimol-activated Currents in the Neurons Freshly Isolated from Rat DRG 巴氯芬对大鼠新鲜分离DRG细胞异四氢烟酸及蝇蕈醇激活电流的抑制作用
Conclusions Baclofen can promote the rehabilitation of the bladder function for incomplete injury of spinal cord with urinary dysfunction. 结论力奥来素可促进脊髓不全损伤排尿障碍患者膀胱功能的恢复。
Mechanism for baclofen inhibition on quantal glutamate release in spinal dorsal horn neurons 氯苯氨丁酸抑制脊髓背角神经元谷氨酸量子释放的机制
Baclofen had the effect of decreasing blood pressure depress in rats with stress-induced hypertension. 结论:氯苯氨丁酸能够降低正常和应激大鼠血压,有剂量依赖性,氯苯氨丁酸对应激性高血压具有降压作用。
Effect of baclofen on the cardiovascular function of rats with chronic stress 氯苯氨丁酸对慢性应激大鼠心血管功能的影响
Effect of baclofen on analgesia in the rat with chronic neuropathic pain Baclofen对慢性神经痛大鼠镇痛效果的影响
Baclofen was more effective in inhibiting field potentials than GABA. 继而,左旋巴氯芬抑制场电位作用强于GABA。
CONCLUSION: Baclofen combined with rehabilitation therapy can effectively relieve spasticity and improve the motion range of joint, motor function and ADL of the stroke patients with spastic hemiplegia. 结论:巴氯酚结合康复治疗能明显改善脑卒中偏瘫肢体的痉挛状态,提高患者的关节活动度、运动功能和生活能力。
Comparative study on Baclofen and Verapamil in the treatment of spastic bladder after spinal cord injury Baclofen与异搏停治疗脊髓损伤后痉挛性膀胱的对比研究
AIM: To analyze the cause of weakening Baclofen effect in treating brain derived muscular spasm and explore what we should pay attention to in the application of Baclofen. 目的:分析影响巴氯芬缓解脑源性肌痉挛效果的原因,探讨巴氯芬应用中的注意事项。
Cause analysis of weakening Baclofen effect in treating brain-derived muscular spasm 影响巴氯芬缓解脑源性肌痉挛效果的原因分析
The pretreatment of atropine can completely abolish the acceleration of muscimol and baclofen on the GABA uptake of stomach slices. 但是,阿托品预处理使蝇蕈醇和β-氯苯氨丁酸促进胃切片3H-GABA摄取的效应完全消失。
Objective To explore the effect of Baclofen on the muscular tension after the cerebrovascular diseases. 目的观察巴氯芬对脑血管疾病后肌张力增高的改善,从而反映其对脑血管病后早期康复的作用。
The clinical effect on hemiplegic muscle spasticity with Baclofen treatment plus comprehensive rehabilitation therapy 巴氯芬联合综合康复疗法治疗偏瘫肌痉挛的临床疗效分析
In stress group and stress with baclofen injecting group, some neurons of hippocampus were degenerated, i.e. the nucleus became shrinking, swelling of mitochondrion with crista broken, myelin sheath became irregular, and synapse became unclear. 结果表明,单纯应激组和应激+baclofen组大鼠海马神经元都有一定的变性改变,如出现了细胞核固缩、线粒体肿胀和线粒体嵴断裂、髓鞘变形,突触结构不清等;
Baclofen belongs to the neurotransmitter pharmaceutical, which is the fat-soluble derivate of γ-aminobutyric acid and it always been adopted in the cure of relaxation of skeletal muscle, hyperkinesias and some traumatic injuries. 巴氯芬是γ-氨基丁酸的脂溶性衍生物,属于神经递质类药物。主要用于骨骼肌松驰,解痉挛及外伤等。
Baclofen caused the blue shift of the maximum of UV absorption peak of pepsin. 观测到巴氯芬使胃蛋白酶的最大紫外吸收峰蓝移。
The secondary structure of cytochrome C have been influenced by both baclofen and γ-aminobutyric acid and then loosen its structure. 红外光谱结果表明巴氯芬及γ-氨基丁酸对细胞色素C的二级结构产生了影响,而使细胞色素C的结构松散。
Being improved by fluorescence spectra and UV spectra, we are assured that the binding interactions between baclofen and BSA were not belonging to the unradioactive resonate energy transfer. 荧光光谱法和紫外光谱法研究表明:巴氯芬与牛血清白蛋白结合的结合不属于非辐射共振能量转移。
Meanwhile, according to the non-radiation energy transfer theory, there is a energy transferring between pepsin and baclofen, so the fluorescence intensity of pepsin was quenched. 根据非辐射能量转移理论,胃蛋白酶与巴氯芬之间发生了能量转移,从而使胃蛋白酶发生了荧光猝灭。
It was also found that application of Baclofen, a GABA_B agonist, can inhibit the calcium current isolated by TEA and TTX in a few of VHCs I ( 9/ 128). 运用GABAB的激动剂Baclofen可以抑制抑制某些VHCsⅠ(9/128)内由TEA和TTX分离到的钙离子电流。
FT-IR spectroscopy was used to investigate the effect of baclofen on pepsin. The results showed that the secondary structure of pepsin has been changed by baclofen. 用红外光谱法研究了巴氯芬对胃蛋白酶的影响,结果表明,巴氯芬改变了胃蛋白酶的二级结构。
The binding interaction between baclofen and pepsin was studied by ultraviolet absorption and fluorescence spectra. 采用荧光光谱法和紫外可见吸收光谱法研究了巴氯芬与胃蛋白酶的结合。
Explored the combine of baclofen with cytochrome C and found that reactant baclofen could make cytochrome C having a hyperchromic effect. 研究了巴氯芬与细胞色素C间的结合。巴氯芬能够使细胞色素C发生增色效应。
Measured by the FT-IR spectroscopy, it was the result that both baclofen and γ-aminobutyric acid could change the secondary structure of BSA. 通过红外光谱法表征可得,巴氯芬和γ-氨基丁酸都能够改变牛血清白蛋白的二级结构。