Determination of Benproperine Phosphate in Human Plasma by RP-HPLC RP-HPLC法测定人血浆中磷酸苯丙哌林的浓度
Determination of benproperine phosphate granules by HPLC HPLC法测定磷酸苯丙哌林颗粒的含量
Preparation and application of benproperine phosphate membrane electrode 磷酸苯丙哌林选择性电极的制备和应用
Some properties and preparations of benproperine phosphate cyclodextrin inclusion compound 磷酸苯丙哌林β-环糊精包合物的性质及制剂开发
Aim To study the synthesis of R (+)-and S (-)-benproperine phosphate and their antitussive activity. 目的合成R(+)和S(-)磷酸苯丙哌林并考察其镇咳活性。
S-benproperine was obtained by submitting the same tosylate to two consecutive S_N2-type reactions with LiBr and piperidine. 与LiBr和***发生两次SN2反应制得S苯丙哌林。
A field-amplified injection procedure was also investigated as a simple and effective way to enhance the sensitivity for the determination, this procedure can improve the detection sensitivity of benproperine phosphate enantiomers up to 23 folds. 实验还尝试采用场放大堆积方法,对磷酸苯丙哌林对映体进行在柱富集,使磷酸苯丙哌林对映体的检测灵敏度提高了23倍。
Under optimum conditions, baseline separation of benproperine phosphate could be obtained. 在优化的实验条件下,磷酸苯并哌啉可获得基线分离。
AIM To investigate the hydroxylation process of benproperine in humans. 目的研究苯丙哌林在人体内的羟基化代谢过程。
OBJECTIVE To study the exchange kinetics of benproperine phosphate-resin complexes. 目的研究磷酸苯丙哌啉药物树脂交换动力学。
R (+)-and S (-)-benproperine phosphate were recrystallized by EtOH. The optical purity was determined by chiral HPLC. R和S苯丙哌林与磷酸成盐,经乙醇重结晶得R(+)和S(-)磷酸苯丙哌林。
Preparation of Hydrophilic Gel Matrices Sustained release Tablets of Benproperine Phosphate 磷酸苯丙哌林亲水凝胶缓释片的制备
Study on metabolites of benproperine using microbial model of transformation 利用微生物转化模型研究苯丙哌林的代谢产物
Object: To establish a method for the content determination of benproperine phosphate granules. 目的:建立磷酸苯丙哌林颗粒含量测定方法。