Benzbromarone can be used in patients with mild to moderate renal insufficiency on a named patient basis but carries a small risk of hepatotoxicity. 苯溴马龙能用于轻中度肾功能不全的患者,但有引起肝毒性的轻度危险性。
Conlusion: As same as Narcaricin mite, the domestic Benzbromarone is an effective and safe uricosuric medicine and is convenient to use. 结论:国产苯溴马龙胶囊是一强力排尿酸药,使用方便安全。
Objective: To evaluate the efficacy and safety of domestic Benzbromarone in the treatment of hyperuricaemia. 目的:评价国产苯溴马龙胶囊治疗高尿酸血症的有效性与安全性。
Objective: To study the efficacy of the "Tong Feng ⅰ" capsule combined with Benzbromarone on chronic uric acid nephropathy ( CUAN). 目的:研究中药复方痛风Ⅰ号胶囊治疗慢性尿酸性肾病的临床疗效。
Benzbromarone was synthesized from salicylaldehyde by condensation with chloroacetone, reduction, acylation, demethylation and bromination with 40.6% overall yield. 以水杨醛为原料,经缩合、还原、酰化、脱甲基、溴化反应制得苯溴马隆,总收率40.6%。
The structure, property, indication, side-effect and clinical evaluation of several bromine-contained medical products are introduced, i.e. bromhexine hydrochloride, ambroxol hydrochloride, benzbromarone and scopolamine butylbromide. 介绍几种含溴药品盐酸溴己新、盐酸氨溴索、苯溴马隆、丁溴东莨菪碱的结构和性质、适应证和副作用以及临床评价。
Investigation of Benzbromarone in Management of Elderly Patients with Hyperuricemia 老年高尿酸血症患者立加利仙应用的探讨
Studies on the Quality of Benzbromarone and Its Impurities 苯溴马隆及其杂质的质量研究
A Randomized Controlled Study of Benzbromarone and Probenecid in the Treatment of Gout 苯溴马龙与磺丙舒治疗痛风的随机对照研究
Determination of Benzbromarone in human plasma by ion-pair HPLC 反相离子对HPLC法测定人血浆中苯溴马龙的浓度
A HPLC method for the determination of benzbromarone tablets was established, using a Shim-pack CLC-ODS column with the mobile phase of methanol-water ( 80 ∶ 20), at the detection wavelength of 237 nm. 建立了苯溴马隆片含量测定的HPLC方法。以Shim-packclc-ODS为色谱柱,甲醇-水(80∶20)为流动相,检测波长为237nm。