Characterization of ca~ 2+/ cam dependent PK II from mouse brain and inhibition on ca~ 2+/ cam dependent PK II activity by Bepridil 小鼠脑Ca~(2+)/CaM依赖性蛋白激酶Ⅱ的鉴定及苄普地尔对其酶活力的抑制作用
Effects of bepridil, nimodipine and nicardipine on the activity of CaM dependent protein kinase ⅱ from mouse cerebrum in vitro 苄丙咯、尼莫地平和尼卡地平对小鼠脑钙调蛋白依赖性蛋白激酶Ⅱ活力的影响
By observing the effects of bepridil on action potential duration ( APD) and main currents involved in the depolarization and repolarization of isolated guinea pig ventricular myocytes, we try to understand the mechanisms of QT prolongation and polymorphic ventricular arrhythmias induced by the drug. 为观察bepridi1对豚鼠单心室肌细胞动作电位时程(APD)及动作电位形成过程中主要离子流的作用,探讨其诱发长QT间期及多形性室性心动过速的电生理机制。
Deformed Effect of Bepridil on Mice Embryo 苄普地尔对小鼠的致畸作用
The cellular Dox accumulation was markedly increased in the presence of bepridil in MDR cells. 苄丙洛能显著地增加MDR细胞内Dox的积累。
Non-competitive Inhibition of Bepridil on Rat Myocardial Sarcolemma Ca  ̄( 2+), Mg  ̄( 2+)-ATPase 苄普地尔对大鼠心肌质膜Ca~(2+),Mg~(2+)-ATP酶的非竞争抑制作用
Irreversible chemical reaction-diffusion equation synthesis of Bepridil 不可逆化学反应扩散方程
The effect of Bepridil on experimental myocardial infarction caused by high level double ligation of left anterior descending coronary artery in rabbits 苄丙咯对结扎家兔冠状动脉造成实验性心肌梗塞的影响
Reversal of multidrug resistance and its mechanism by bepridil 苄丙洛逆转肿瘤多药抗药性作用及其机理的探讨
Inhibitory Effects of Cicletanine and Bepridil on the Contractions of Isolated Rat Thoracic Aorta Rings Cicletanine与Bepridil对大鼠离体胸主动脉环收缩的抑制效应
Aim: To explore the reversal of multidrug resistance ( MDR) and its mechanisms by bepridil which is a new calcium channel blocker. 目的:为了探讨新的钙阻断剂苄丙洛逆转肿瘤多药抗药性(MDR)的作用及其机理。
The deformed embryo had little differentiation of HGC or with incomplete differentiation. Deformed Effect of Bepridil on Mice Embryo 畸形胚胎头部表皮细胞中很少有HGC的分化或HGC分化不完全,其形态结构也呈现畸形。苄普地尔对小鼠的致畸作用
No effect was observed for ADR accumulation in the high or concentration. And cellular free calcium ion was not changed by bepridil in MDR cells. 高钙或低钙离子浓度不能改变MDR细胞内Dox积累,苄丙洛也不能改变MDR细胞内游离钙离子浓度。