Efficacy and safety of homemade bezafibrate in treatment of hypertriglyceridemia 国产苯扎贝特治疗高甘油三酯血症的疗效及安全性
A post hoc analysis was used to examine the effect of bezafibrate on progression to use of oral antidiabetic medications or insulin in individuals with diabetes at baseline. 采用事后分析以口服抗糖尿病药或胰岛素做基准检测苯扎贝特的效果。
The effects of homemade Bezafibrate on abnormal metabolism of glucose and lipid in patients with high serum triglycerides level. Study on abnormal glucose metabolism in hyperglycemia post acute ischemic stroke patients 国产苯扎贝特对高三酰甘油血症脂代谢及糖代谢影响的研究急性缺血性脑卒中后高血糖患者糖代谢异常的研究
Randomized controlled trials should be considered to assess the utility of bezafibrate in treating patients with diabetes or in preventing diabetes in high-risk patients. 应该考虑随机对照临床试验来评价苯扎贝特治疗糖尿病或者预防高危人群患糖尿病的功效。
Determination of Bezafibrate Tablets in Human Plasma by HPLC Application to Bioequivalent and Pharmacokinetic Studies 高效液相色谱法研究人体内苯扎贝特片的药动学和生物等效性
Effects and Mechanism of Bezafibrate on Expression of Endothelial Nitric Oxide Synthase in Human Umbilical Vein Endothelial Cells Induced by Oxidized Low Density Lipoprotein 苯扎贝特对脐静脉内皮细胞内皮型一氧化氮合酶表达的影响及机制
A Comparative Study on the Quality of Trail-product Bezafibrate Sustained-release Tablets with Foreign Commercial Product 试制苯扎贝特缓释片与国外市售品质量对比研究
Optimization of the Formulation of Bezafibrate Osmotic Pump Tablets by Central Composite Design-response Surface Methodology 星点设计-效应面法优化苯扎贝特渗透泵片处方
The Influence of Apoptosis on Pancreatic β Cells of Obese and Type-2 Diabetic Rats by Bezafibrate Treatment 苯扎贝特对肥胖和2型糖尿病大鼠胰岛β细胞凋亡的影响
CONCLUSIONS& Bezafibrate appears to have clinically important antidiabetic properties. 结论:苯扎贝特表现出很重要的临床抗糖尿病属性。
Effects of Bezafibrate on the eNOS Expression of Cultured Endothelial Cells Induced by ox-LDL and the Role of LOX-1 苯扎贝特对ox-LDL所诱导的人脐静脉内皮细胞eNOS表达的影响及其机制
Effects of Bezafibrate on the Expression of Caveolin-1 and the Proliferation of Smooth Muscle Cells Induced by Platelet-Derived Growth Factor 苯扎贝特对血小板源生长因子诱导的血管平滑肌细胞增殖和小凹蛋白1表达的影响
Objective: To investigate proliferation and migration effects of bezafibrate as well as relevant signaling mechanism. 目的:苯扎贝特对牛主动脉内皮细胞(BAECs)增殖和迁移的影响及信号转导机制。
RESULTS: The clinical efficacy of bezafibrate for total cholesterol ( TC) and triglycerides ( TG) were 84% and 88%; 结果:苯扎贝特降低血胆固醇(TC)和三酰甘油(TG)的总有效率为84%和88%。
Bezafibrate stimulate endothelial cell growth and miration 苯扎贝特促进内皮细胞的增殖和迁移
Effect of bezafibrate on incidence of type 2 diabetes mellitus in obese patients 苯扎贝特对肥胖患者2型糖尿病发病率的影响
Treatment of hyperlipoproteinemia with bezafibrate in 20 patients 苯扎贝特治疗高脂蛋白血症20例
Conclusion Bezafibrate may improve metabolic abnormalities of middle-senior aged patients. 结论苯扎贝特有可能改善中老年高血压代谢综合征患者的多种代谢异常因素。
Improve on the Synthetic Process of Bezafibrate 苯扎贝特的合成工艺改进
Methods: Bezafibrate pellet capsules were prepared by centrifugal granulation technology. 方法:采用离心造粒技术制备苯扎贝特缓释微丸胶囊;
CONCLUSION The method appeared to be rapid, sensitive and accurate, and can be used for determination of residual organic solvent in bezafibrate. 结论本法快速、灵敏、准确,可用于原料药苯扎贝特中残留溶剂的检测。
Effect of antihyperlipidemic drug bezafibrate on glucose metabolism 降脂药物&必降脂对糖代谢的影响
In this study, the metabolic stability of commonly used fibrates ( gemfibrozil, clofibrate, fenofibrate, bezafibrate) were investigated using rat and human liver microsomes. 本课题研究了经常使用的几个贝特类药物(吉非罗奇、氯贝特、菲诺贝特、本扎贝特)在大鼠和人的肝微粒体中的代谢稳定性。