Therefore bombesin has become a promising target of anti-tumor therapy. 已成为抗肿瘤治疗的一个有希望的靶点。
Study of the Effect of Bombesin on Bacterial Translocation Following Small Bowel Transplantation in Rats; Intraoperative Care in Repair of Defects Around the Ankle with Sural Neurovascular Flap for Children 蛙皮素防治小肠移植术后细菌移位的实验研究儿童腓肠神经营养血管皮瓣移植术的手术配合
Objective: To study the effects of bombesin on bacterial translocation in rats after hemorrhage combined with infection. 目的:研究蛙皮素(BBS)对失血感染模型大鼠肠黏膜屏障和肠道细菌移位的影响。方法:从颈静脉插管放血制成单纯失血模型;
The regulatory effects of bombesin on the activities of disaccharidase in the intestinal mucosa in neonatal rabbits 小肠刷状缘水解酶与大肠癌蛙皮素对新生兔小肠粘膜刷状缘双糖酶活性的调节作用
When the outer circumstance temperature altered, function of Bombesin to animals changed too. 当外界环境温度不同时,蛙皮素对动物体温的作用不同。
Aims: To investigate the effects of bombesin on the malignant transformation of immortalized human gastric epithelial cell line GES-1 induced by chemical carcinogen N-methyl-N ′-nitro-N-nitrosoguanidine ( MNNG). 目的:探讨蛙皮素在化学致癌剂N鄄甲基鄄N'鄄硝基鄄N鄄亚硝基胍(MNNG)诱发人胃黏膜上皮永生细胞系GES鄄1癌变过程中的作用。
Inhibition of Bombesin to IL-1 β-induced Fever and Effects on cAMP Level in Hypothalamus and Plasma BN对IL-1β致热的抑制作用及下丘脑和血浆cAMP的影响
GES-1 cell line was incubated with varying concentrations of bombesin with or without its antagonist and growth of the cell line was determined. 观察不同浓度的蛙皮素及其受体拮抗剂对GES1细胞生长的影响。
In this study, the mechanism underlying thermoregulatory action of bombesin is to be further elucidated. 本文旨在探讨蛙皮素的降体温及抗热作用机制。
Effect of bombesin on proliferation, adhesion, immigration of human androgen-independent prostate cancer cells line 蛙皮素对雄激素非依赖型前列腺癌细胞增殖、粘附、迁移的影响
Study on the Regulatory Effects of Bombesin on the Gastrointestinal Morphology and Proliferation of Mucosa Cells in Neonatal Rabbits 蛙皮素对新生兔胃肠形态及细胞增殖的调节研究
Inhibition of Bombesin to IL-1 β-induced Fever and Effects on PGE_2 Level in Hypothalamus and Plasma BN对IL-1β致热的抑制作用及对POA和血中PGE2的影响
A immunohistochemical and image analytic study of bombesin in gastric carcinoma and its adjacent gastric mucosa 胃癌、癌旁粘膜中蛙皮素的免疫组化及图像分析研究
Conclusion: Bombesin may play an important role in the proliferation, production of intracellular cAMP, and activity of PKC in poorly differentiated gastric carcinoma cell line BGC-823. 结论:BBS对胃癌细胞BGC-823的生长、细胞内cAMP产生及PKC活性增加有重要作用。
CONCLUSION: Bombesin can inhibit IL-1 β-induced fever at 4 ℃, and the mechanism may be related to the inhibition the synthesis and release of cAMP. 结论4℃时蛙皮素能抑制IL-1β发热,其机制有可能是通过抑制cAMP合成或释放实现的。
Conclusions Besides somatostatin receptors, most of gastrinomas and VIPomas also express receptors for bombesin, secretin and vasoactive intestinal peptide. 结论除生长抑素受体外,胃泌素瘤和肠血管活性多肽瘤还表达胰泌素、蛙皮素、肠血管活性多肽受体。
In serum-free medium, bombesin receptor antagonist inhibited the growth of human gastric cancer cells. 在无血清培养基中,上述受体拮抗剂对人胃癌细胞生长也有直接的抑制,提示蛙皮素对胃癌细胞有自分泌调节作用。
The Relationship between Non-cholinergic, Late Slow-excitatory Postsynaptic Potential and Bombesin or Substance P in Sympathetic Ganglia of Guinea-pig 豚鼠交感神经节非胆碱能迟慢兴奋性突触后电位与蛙皮素、P物质的关系
Effects of bombesin and somatostatin on proliferation of human gastric cancer cell line BGC-823 and their postreceptor signal transduction 蛙皮素和生长抑素对人胃癌BGC-823细胞生长的影响及受体后信息传递
The Effect of Bombesin on the Growth of Human Gastric Carcinoma Cell Line and Human Immortalized Gastric Epithelial Cell Line and Its Mechanisms 蛙皮素对人胃癌细胞株和人胃粘膜上皮永生细胞株生长的影响及作用机制的研究
Lung cancer cells and bombesin inhibit dendritic cell generation and function 肺癌细胞和蛙皮素抑制树突状细胞的产生和功能
Objective To investigate the regulatory effects of bombesin on the gastrointestinal morphology and proliferation of mucosa cells in neonatal rabbits. 目的探讨蛙皮素对新生兔胃肠形态学及胃肠粘膜细胞增殖的调节作用。
Objective To investigate the regulatory effects of bombesin on the activities of disaccharidase in the intestinal mucosal cells in neonatal rabbits. 目的探讨铃蟾肽对新生兔小肠黏膜双糖酶活性的影响。
Objective: To observe the effect of bombesin on cytoskeleton form and intracellular free calcium ( [ Ca~ 2+] I) concentration in PC-3 prostate cancer cell line. 目的:观察蛙皮素(BBS)对前列腺癌PC-3细胞骨架形态及细胞内游离Ca2+([Ca2+]i)浓度的影响。
The opioids, and the gastrin-releasing peptide/ bombesin group; 阿片样物质;胃泌素释放肽/蛙皮素家族;
Radiolabeled analogs of alpha-melanocyte-stimulating hormone, neurotensin, vasoactive intestinal peptide, bombesin, substance P, neuropeptide Y, gastrin and cholecystokinin are also being developed and evaluated in vitro and in vivo. 现已成功开发出放射性核素标记的α-黑色素细胞刺激激素、神经紧张素、血管活性肠肽、铃蟾肽、P物质、神经肽Y、缩胆囊素类似物等,并已进行体内、外研究。
The mechanism regulating cell growth and proliferation by bombesin is not very clear. 蛙皮素促进细胞生长及细胞转化的许多机制尚不清楚,与细胞周期调控因子之间的关系亦未见报道。
Bombesin is a 14 amino acid GI peptide with growth factor-like effects. Studies in recent years showed that bombesin has trophic effect on many kinds of cell lines and tissues, especially on tumor cell lines. 蛙皮素(Bombensin)是由14个氨基酸组成的具有生长因子样作用的胃肠肽,对多种细胞和组织都有营养作用,尤其是对肿瘤细胞的促生长作用逐渐引起人们的关注。