Objective: Observe the effect of Yueju pill to chronic unpredictable mild stress ( CUMS) mouse, to reveal the drug action and the mechanism of the medicine. 目的:观察越鞠丸对慢性轻度不可预见性的应激抑郁(CUMS)小鼠模型的影响,揭示该方对抑郁症的药效及作用机理。
Our Server Erects and Cums into Memory 服务器正在与内存数据接入
Aerobic exercise protects rats with chronic unpredictable mild stress against acute stress 有氧运动对急应激暴露下CUMS大鼠的保护作用
Effects and Possible Mechanisms of Estrogen on Behavior of Depressed Rats Induced by CUMS 雌二醇对慢性应激抑郁大鼠行为的影响及其可能的机制
Objective To study the validity, reliability and utility of the chronic unpredictable mild stress model of depression ( CUMS). 目的探讨慢性轻度不可预见性的应激抑郁模型建立的可行性和此模型的有效性。
Analysis of a Piston Trouble in Cums Diesel Engine CUMS柴油机的一例活塞故障分析
Effect and Possible Mechanism of Habenular Nucleus in the Regulation of Adenosine on Behavior of Depressed Rats Induced by CUMS 缰核参与腺苷对慢性应激抑郁大鼠行为的影响和可能机制
Methods The depression model rat was produced by CUMS, and the therapy effect of BCPT was observed in CUMS rats. We detected the body weight, sweet water wastage and crossing score, rearing score of rats by open field test. 方法:采用CUMS法,造成大鼠抑郁模型,定期测量BCPT对该模型大鼠的体重及糖水消耗量,以开野实验的方法测定大鼠水平及垂直活动。
Harm of Crack and Leakage of Oil Cooler Core in K-19 Model CUMS Diesel Engine K-19型CUMS柴油机机油冷却器芯子裂漏故障的危害及解决办法
Bjective: Chronic unpredicted mild stress was taken to establish rat depression model. To investigate the effect of nimesulide on the depressive-like behaviors caused by chronic mild unpredictable mild stress ( CUMS) in rats. 目的:本实验采用慢性不可预见性温和应激(Chronicunpredictablemildstress,CUMS)建立大鼠抑郁模型,观察尼美舒利对慢性应激大鼠抑郁行为的影响。
However, CUMS is made by manual operation, so there are big workload and human factors. 然而,慢性温和应激模型造模过程采用人工操作,存在工作量大、人为因素影响多等缺点。
Method Thirty-two adult male Wistar rats were randomly divided into four groups: the control group, the CUMS model group, the labetalol group and the exercise group, with eight rats in each group. 方法32只成年雄性Wistar大鼠随机分为对照组、CUMS组、拉贝洛尔组、有氧运动组,每组8只。
Meanwhile, the average intragastric pressure and the magnitudes of gastric contraction were significantly declined ( p0.01) after 21 days CUMS. 同时大鼠平均胃内压和胃的收缩幅值也显著降低(p<0.01)。
Now, Chronic unpredictable mild stress ( CUMS) is the animal model that is the most closely to the clinical depression. 慢性温和应激刺激模型是目前与临床抑郁机制最为接近的动物模型。
In the present study, we observed both the expression of hippocampal synapsin I and depression-associated behavior in a rat model of depression induced by chronic unpredictable mild stress ( CUMS). 当前的研究中,我们观察了CUMS抑郁症模型大鼠海马synapsinⅠ的表达情况,同时还观察了抑郁症相关行为。
Conclusion ( 1) CUMS could lead the depressive behavior changes of rats, and aggravate the damages of the hippocampus and prefrontal cortex. 结论(1)CUMS可导致大鼠产生抑郁性行为,加重海马与前额叶皮层细胞应激损伤。
And it also alleviated the weight losing in the CUMS model mice. ( 2) Xiaoyao Powder had no effect on locomotor activity in mice in its effective dose range. 2. 并对模型动物体重的减轻有对抗作用。(2)逍遥散在有效剂量下不影响小鼠的自主活动。
Objective: To investigate the effect of caffeic acid on depressive behavior in chronic unpredictable mild stress ( CUMS) rat and preliminary explore its mechanism. Methods: Chronic unpredictable mild stress was used to establish the rat model of depression. 目的:观察咖啡酸对CUMS大鼠行为学的影响并初步探讨其机制。方法:采用各种慢性不可预见性轻度刺激(Chronicunpredictablemildstress,CUMS)建立大鼠抑郁模型。