Objective: To study the expression and the effect of TGF_ β and VEGF on the repairing bone defects and the combination of musculoperiosteal flap, bone marron and spongy bone granules in transplanted to repair the bone defects. 目的:分析转化生长因子(TGF)与血管内皮生长因子(VEGF)在肌肉骨膜瓣,松质骨颗粒及骨髓联合移植修复骨缺损中的表达及机理。