sulindac
英
美
网络 舒林酸; 苏灵大; 硫茚酸; 服用舒林酸; 舒比酸
双语例句
- Objective To assess the efficacy and safety of sulindac on colorectal polyps.
目的评价舒林酸治疗结直肠息肉的有效性和安全性。 - A study of the effects of PPAR γ pathway on the proliferation inhibition of gastric cancer cells by sulindac and the underlying mechanism
PPARγ通路在舒林酸抑制胃癌细胞增殖中的作用及机制 - Objective: To research the mechanism of sulindac affecting human colorectal cancer cells.
目的探讨三根祛瘤方（简称三根方）对结肠癌细胞的作用机制。 - Conclusion The therapeutic effect of sulindac on FAP is not sure, but it is effective on SCAP.
结论系统评价结果显示舒林酸对于家族性FAP的疗效尚不确切，而对SCAP有一定的疗效。 - Background& aim: to study the effect of Sulindac on growth inhibition of human gastric cancer cells bgc_823 in vitro and its antineoplastic mechanisms.
背景与目的：体外研究舒林酸对人胃癌bgc-823细胞的生长抑制作用，探讨其作用机制。 - Conclusions: Sulindac may inhibit the proliferation and induce apoptosis of colon cancer cell HT-29, and its mechanism probably relates to the progress of its prevention on cell cycle.
结论：舒林酸可抑制结肠癌细胞株HT-29生长，其机制可能与其阻止细胞周期的进展，诱导细胞凋亡有关。 - Effect of sulindac on growth of transplantable ovarian carcinoma of nude mice model
舒林酸对卵巢癌裸鼠腹腔移植瘤生长的影响 - OBJECTIVE To observe the therapeutic effects of sulindac ( a new type of NSAIDs) on experimental hypercalciuria and to clarify its pharmacological mechanism.
目的：观察新型非类固醇类抗炎药&舒林酸对实验性高钙尿症的防治作用，探讨其可能机制。 - Objective This study was conducted to assess the growth inhibition of colorectal adenoma cells by sulindac and identify the possible mechanisms.
目的研究非甾体抗炎药苏林酸对大肠腺瘤细胞的生长抑制作用及其机制。 - Objective: To observe the effect of Sulindac on changes of the apoptosis regulating genes in different stages of the tumor formation, and probe the possible anticarcinogenic molecular mechanism of sulindac.
目的：本实验通过观察舒林酸对凋亡调控基因的影响，初步探讨舒林酸防治肿瘤作用可能存在的分子机制。 - Preparation and Clinical Application of Sulindac Chitosan Gel
舒林酸壳聚糖凝胶的制备与临床应用 - Analysis of 48 cases of esophageal cancer treated by sulindac stents combined radiotherapy
舒林酸食道支架放疗联合治疗食道癌48例分析 - Inhibitory effect of sulindac on the growth of gastric cancer cells in vitro
舒林酸抑制胃癌BGC-823细胞生长的实验观察 - Sulindac Induced Apoptosis of HT-29 Colon Adenocarcinoma Cell
苏林酸诱导结肠腺癌HT-29细胞凋亡的实验研究 - The Growth Inhibition of Colorectal Adenoma Cells by Sulindac and Its Mechanisms
苏林酸对大肠腺瘤细胞的生长抑制作用研究 - Nonsteroidal anti-inflammatory drugs ( NSAIDs), such as aspirin, indomethacin and sulindac, showed by lots of evidence, have the effect of suppressing tumor proliferation and inducing apoptosis besides its effect of anti-inflammation, relieving pain, and anti-coagulation of platelets.
大量研究证据表明，非甾体类抗炎药（nonsteroidalanti-inflammatorydrugs，NSAIDs）具有抗肿瘤增殖和诱导肿瘤细胞凋亡的作用，长期服用阿司匹林可以显著降低结肠腺癌的死亡率。 - No severe adverse event was found during the treatment. Conclusions Long-term treatment of sulindac is effective in maintaining the regression of colorectal adenoma in FAP patients.
结论舒林酸长期维持治疗可使FAP患者结直肠腺瘤保持长期显著消退状态。 - Conclusion Sulindac has inhibitory effects on S180, and it decreases the expression of COX-2 in tumor tissue. There is positive relation between the expression of COX-2 and angiogenesis related factor.
结论苏灵大对S180移植性肿瘤有抑制作用，其作用途径可能是通过抑制COX-2的表达而抑制肿瘤血管的形成，进而抑制肿瘤的生长。 - A Study on the Apoptosis of BGC-823 Gastric Cancer Cells Induced by Sulindac
舒林酸诱导胃癌BGC-823细胞凋亡的研究 - Flow cytometry, transmission electron microscopy and DNA electrophoresis all demonstrated that sulindac could induce apoptosis of the HT-29 cell line in a time-and dose-dependent manner.
结果：流式细胞术、DNA电泳和透射电镜观察均显示苏林酸可诱导HT－29细胞凋亡，且具有时间和剂量依赖性。 - Experimental study for effect of sulindac for gastric cancer cell BGC-823
舒林酸对胃癌细胞株BGC-823作用的实验研究 - Effects of Sulindac on growth inhibition and apoptosis induction in human gastric cancer cells
舒林酸抑制人胃腺癌细胞增殖及诱导凋亡 - Conclusion The proliferation of SGC-7901 cells was inhibited after treated by sulindac and nimesulide. Suppressing COX-2, NF-κ B expression may play some roles in the antitumor process of these two drugs.
结论舒林酸、尼美舒利可以抑制人胃癌SGC-7901细胞增殖，抑制NF-κB，COX-2的蛋白表达在二者抑制肿瘤机制中可能具有一定作用。 - The expression of COX-2 in the tumor tissue was also inhibited by sulindac. And accordingly the expression of VEGF, FGF-2 and MVD was also markedly inhibited by sulindac with dose dependence.
免疫组化结果显示苏灵大对肿瘤组织的COX-2表达有明显的抑制作用，同时血管生长相关因子VEGF、FGF-2表达也明显下降，MVD明显降低。 - Objective To assess the clinical efficacy of sulindac on familial adenomatous polyposis ( FAP) and its possible mechanism.
目的观察舒林酸对家族性腺瘤息肉病（FAP）的临床疗效，并探讨其可能的作用机制。 - ABSTRACTS OF ORIGINAL ARTICLE Relative bioavailability of sulindac capsules
口服舒林酸胶囊剂和片剂的相对生物利用度 - At last, in the two systems of SDS-MECC and Tween 20-MECC, the contents of sulindac and indometacin in tablets were determined and satisfactory results were obtained.
在SDS和Tween20MECC体系下，分别进行了实样测定，取得了满意的结果。 - Methods SGC-7901 cells were treated by sulindac and nimesulide. The anti-proliferative effect was measured by using MTT assay; COX-2 and NF-κ B protein expression were examined by immunohistochemical stain and western-blot analysis.
方法对人胃癌SGC-7901细胞采用细胞培养，MTT法检测不同浓度舒林酸、尼美舒利对人胃癌SGC-7901细胞增殖抑制作用，免疫组化、westernblot方法检测药物对COX-2、NF-κB表达的影响。 - In recent years, Accumulating evidences have indicated that sulindac appears to reduce the risk of colorectal cancer, decrease the incidence of familial adenomatous polyposis. Compared with other traditional nonsteroidal anti-inflammatory drugs, sulindac has less adverse reactions.
它对肾脏及胃肠道的不良反应均小于其它传统的非甾体抗炎药。近年来，有很多研究证实舒林酸同时具有降低结直肠肿瘤及家族性结肠息肉的作用。