tacrine
英
美
网络 他可林; 他克林; 乙酰胆碱酯酶抑制剂特可林; 乙酰胆碱酯酶抑制剂他可林; 胆碱酯酶抑制剂他克林
双语例句
- The safety of tacrine has not yet been proven, and there is concern that it causes damage to the liver.
他克林的安全性尚未得到证实，有人担心它会对肝脏造成损害。 - OBJECTIVE: To synthesize Tacrine, a new drug for the treatment of Alzheimer ′ s disease.
目的：合成抗早老性痴呆药他克林。 - Comparision of pharmacokinetics of tacrine between young rats and aged rats
盐酸他可林在不同月龄大鼠体内的药物动力学比较 - Aim To synthesize acylated prodrug of tacrine hydrochloride ( THA) to improve the infiltration ability across the blood brain barrier ( BBB).
目的制备盐酸他克林（THA）的酰化前体药物以提高其透过血脑屏障（BBB）的能力。 - Results Amnesia in mice can be prevented markedly after huperzine-A 0.4mg/ kg, Tacrine 40mg/ kg or Galanthamine 4.0mg/kg is administered.
结果ig石杉碱甲0.4mg／kg或他克林40mg／kg或加兰他敏4.0mg／kg均能使小鼠的记忆障碍得到显著的改善。 - Inhibition of tacrine on delayed rectifier and transient outward potassium currents in cultured rat hippocampal neurons
他克林对培养大鼠海马神经元延迟整流钾电流和瞬间外向钾电流的影响 - Theoretical studies on the mechanism of inhibiting ache by tacrine and its analogues
他克林及其类似物抑制乙酰胆碱酯酶机理的理论研究 - Tacrine in treatment of Alzheimer disease: a multicenter, double-blind study in China
他克林治疗阿尔采末病：在中国的多中心双盲研究 - Tacrine is a selective acetylcholinesterase ( AChE) inhibitor which has serious liver toxicity.
静脉用胺碘酮致严重肝功能损害一例他克林是一个选择性较好但毒副作用明显的乙酰胆碱酯酶抑制剂。 - Objective: To investigate the mechanism of liver injury of Tacrine and cell toxicity of several ginsenosides.
目的：探讨他克林的肝损伤机理及人参皂苷的活性筛选。 - Bioactive conformations were generated by docking a series of Tacrine Dimers Analogs with AChE crystal structure.3D quantitative structure activity relationship ( 3D-QSAR) models were developed for AChE inhibitors using modeling analysis.
化合物的活性构象是通过一系列他克林二联体化合物与AChE晶体结构进行对接而获得的，以此进行建模分析，建立结构与活性之间的三维定量构效关系。 - Despite this limitation, tacrine has been widely used as scaffold for the development of new multifunctional agents with additional biological properties other than AChE inhibition.
尽管如此，他克林仍被作为骨架广泛的应用于开发除了AChE抑制作用以外还具有其它生物特性的多功能药物。