The derivatives etoposide and teniposide have been successfully utilized in the treatment of a variety of malignant conditions. 依托泊甙、替尼泊甙已经成功地用于临床抗肿瘤治疗。
Teniposide and Nimustine Combination Therapy for Patients with MGMT Negative Gliomas: Experience of 18 cases 替尼泊苷与尼莫司汀联合治疗MGMT阴性表达的恶性胶质瘤:附18例经验
Inhibitory effect of thalidomide combined with low-dose teniposide on transplanted human gastric adenocarcinoma BGC-823 tumor in nude mice 低剂量替尼泊苷联合沙利度胺对人胃癌移植瘤的抑制作用
Teniposide ( VM-26) can inhibit Topoisomerase ⅱ ( Top ⅱ) that induces DNA strand-breaks, and can also block cell circle in the late S nd G2+ M phases. 鬼臼噻吩甙(VM-26)能抑制拓扑异构酶(TopⅡ)使DNA单、双链可逆性断裂,并能使细胞阻滞于S后期和G2+M期。
Objective To study the effect of calcium antagonist nimodipine ( NMD) combined with chemotherapy drugs carmustine ( BCNU) and teniposide ( Vm 26) on chemoresistance in malignant glioma cells and provide rational chemotherapy method in clinical. 目的观察钙离子拮抗剂尼莫地平(NMD)与化疗药物卡氮介(BCNU)及威猛(Vm-26)联合使用对脑胶质瘤细胞化疗耐药性的影响,为临床上脑胶质瘤的合理化疗提供理论依据。
Purpose: To study the antiproliferative effect of tricyclic antidepressant desipramine ( DMI) alone or in combination with chemotherapeutic agent teniposide ( VM 26) against rat C6 glioma cells. 目的:研究三环类抗抑郁药地昔帕明(DMI)对脑胶质瘤C6细胞增殖的调控作用,并探讨与临床常用治疗脑瘤的化疗药物替尼泊苷(VM26)合用的协同效应。
Paclitaxel and Teniposide Combination Chemotherapy for Patients with Malignant Astrocytic Brain Tumors 紫杉醇与替尼泊苷联合化疗治疗脑恶性胶质瘤
A Pharmacokinetic Study of Teniposide in Intraperitoneal Chemotherapy of Ovarian Cancer 替尼泊甙用于卵巢癌患者腹腔化疗的药代动力学研究
Teniposide and lomustine plus combination chemotherapy in the prevention of brain metastasis in lung cancer patients 替尼泊苷和洛莫司汀加用于联合化疗中预防肺癌脑转移
Effect of desipramine alone and in combination with teniposide on proliferation in rat C6 glioma cells 地昔帕明单用和合用替尼泊苷对大鼠脑胶质瘤C6细胞增殖的调控作用
Clinical study of teniposide in combination with cisplatin in treatment of lung cancer 替尼泊甙加顺铂联合治疗肺癌的临床研究
Teniposide and Cisplatin Compared with Etoposide and Cisplatin for Treatment of Small Cell Lung Cancer 替尼泊甙联合顺铂与足叶乙甙联合顺铂治疗小细胞肺癌的疗效比较
The rate of inhibition of teniposide ( VM-26) and etoposide ( VP-16) on ALL cells was higher that on ANLL cells. 替尼泊苷(VM-26)和VP-16对ALL细胞的抑制率高于ANLL细胞;
Chemotherapy with higher or lower dose of teniposide combined with cisplatin and pingyangmycin for oral squamous cell carcinoma 不同剂量替尼泊苷联合化疗方案治疗口腔鳞癌的前瞻性研究
This clinical trial was designed to compare the efficacy and toxicity of teniposide plus cisplatin ( VM 26+ DDP) regimen and EP regimen in treatment of SCLC, and the possible role of VM 26 on prevention of brain metastasis of SCLC. 本研究的目的是观察比较VM-26联合DDP方案与EP方案治疗SCLC患者的疗效及对脑转移的预防作用。
The fluorescence detector measured the Vp-16 and teniposide ( VM-26) with the excitation wavelength of 220 nm and the emission wavelength of 330 nm. 荧光检测以220nm波长激发光及330nm波长检测Vp-16及替尼泊苷(VM-26)。
Chemotherapy wiht teniposide and nimustine in 20 cases with metastatic brain tumors 联合应用替尼泊苷和尼莫司汀治疗20例转移性脑肿瘤
Analysis of Effect of Teniposide Plus CHOP Regimens on Malignant Lymphoma 替尼泊甙方案治疗恶性淋巴瘤疗效分析
Chemosensitivity testing of oral squamous cell carcinomas with teniposide 替尼泊甙对口腔鳞癌化疗敏感性的体外研究
Study on the Mechanism for Topoisomerase ⅱ Poison Teniposide Against Oral Cancer Cells 拓扑异构酶抑制剂替尼泊甙抗口腔癌机制的研究替尼泊甙对口腔鳞癌化疗敏感性的体外研究
OBJECTIVE: To define the activity and toxicity of teniposide in combination with cisplatin in treatment of lung cancer. 目的:研究替尼泊甙加顺铂联合治疗肺癌患者的疗效和毒性。
Methods 23 patients was randomly treated with teniposide plus CHOP regimens. 方法以替尼泊甙联合CHOP方案随机治疗23例恶性淋巴瘤,按全国统一标准评定疗效。
Effect of Combined Chemotherapy with Teniposide on Gastric Cancer Cells 以替尼泊甙为主联合用药对胃癌细胞的作用
Teniposide, cyclophosphamide and dexamethasone combination treatment for stage ⅲ multiple myeloma: a report of 21 cases 鬼臼噻吩甙、环磷酰胺和地塞米松治疗Ⅲ期多发性骨髓瘤21例报告
Objective It is to evaluate the curative effects and the relevant toxicty and side effets on curing brain malignant neuroglioma by using teniposide combination chemotherapy. 目的评价含替尼泊苷联合化疗方案对恶性脑胶质瘤的治疗效果和毒副作用,探讨有效的辅助化疗方案,以期提高恶性脑神经胶质瘤患者的疗效,延长生存期。
Etoposide ( VP-16) and teniposide ( VM-26) are two semi-synthetic derivatives of podophyllotoxin, which have been officially approved for clinical use against various types of cancers including breast cancer, testicular cancer, non small-cell lung cancer, lymphoma and childhood leukemia. 依托泊苷(VP-16)和替尼泊苷(VM-26)是鬼臼毒素的半合成衍生物,在临床上广泛用于乳腺癌、睾丸癌、非小细胞肺癌、淋巴癌、白血病等的治疗。
Thus, the aim of this study was to prepare and evaluate a stable teniposide sub-microemulsion injection ( TSE). An HPLC method was established for the analysis of teniposide in vitro. 本研究的目的是制备并评价一种稳定的替尼泊苷亚微乳注射液(TSE)。本论文建立了替尼泊苷HPLC体外分析方法,该方法重现性好,准确度高。