The researchers constructed the transposons in such a way that they can carry the therapeutic gene into the target cell DNA. 研究人员构建了转位子,通过转位子携带治疗基因进入靶细胞的DNA。
Study on Inheritance Divergence of Transposons in Polyploidy Fish and Gonad Development of Gynogenetic Fish in Molecular Biology 多倍体鱼转座子的遗传变异和雌核发育鱼性腺发育的分子生物学研究
Transposons are mobile DNA elements that can integrate into'foreign'DNA via a'cut-and-paste'mechanism. 转位子是一种移动的DNA分子,它通过可以通过“剪切和粘贴”机制融入异体的DNA分子。
It is believed that DNA methylation has important functions in gene imprinting, for transposons and in vivo retrovirus silencing as well as the stability of the genome; 现在普遍认为DNA的甲基化的功能是参与许多印记基因、失活的X染色体上的基因、转座子和内源的反转录病毒的沉默。
In the period of 1994 to 1999, YANG Wen-Peng isolated a higher lysine mutant from Robertson's Mutator ( Mu) stocks, which contain mutations induced by insertion of Mu transposons. 作者于1994-1999年期间,从Robertson的增变子Mu(Mutator)诱导的玉米突变群体中,分离得到一个高赖氨酸突变。
Mobilization of Transposons m Ping, Ping and Pong and Heritable Alterations in DNA Methylation Pattern Induced by Laser Irradiation in Rice 激光辐射诱导水稻转座子mPing,Ping及Pong的转座激活和可遗传DNA甲基化变异
Sequence analysis indicated that among clones that manifested significant homology to known-function genes are predominantly transposons or retrotransposons, as well as genes encoding for metabolic enzymes. 同源性分析表明,发生遗传和表观遗传变异的序列中具有同源性的序列包括转座子和反转座子以及编码多种酶的基因序列。
Identify Methods for the Genome Sequence Flanking the Transposons 转座子插入位点的鉴定方法
And many catabolic genes are linked to inserted elements or transposons. Therefore, catabolic genes can be rapidly spread. 许多分解代谢基因与插入元件或转座子相连,因此,分解代谢基因可以在细菌间快速传播。
This paper reviewed the developments of plant transposons in gene isolating and cloning, as well as its use in studying gene function in plant. 本文综述了植物转座子及其作为基因分离和克隆工具的研究进展,并讨论其在植物基因功能研究方面的应用。
Insertional mutagenesis using T-DNA, transposons and plasmids are commonly methods to creating a mutant library. 构建插入突变库的方法有T-DNA插入突变、转座子插入突变和质粒介导的插入突变。
As insertional mutagens or molecular tagging, transposons have been widely used for gene isolation, cloning and function study. 转座子作为插入突变源和分子标签被广泛应用于基因的分离和克隆以及基因功能分析,然而至今没有发现非常有效的脊椎动物的转座子。
UV B signaling pathway and specific UV B receptor, DNA damage, activation of transposons, molecular damage of photosynthetic apparatus and UV B regulation of related gene expression were included. 主要讨论了UV-B信号途径及光受体,UV-B诱导的DNA损伤、转座子激活,UV-B对光合器官的分子伤害及相关基因表达的调控等。
Transposition mechanism of the transposons in Bacillus thuringiensis and their relationship with insecticidal crystal protein genes 苏云金芽胞杆菌转座因子的转座机理及其与杀虫晶体蛋白基因的关系
Antibiotic resistance gene have frequently been found to be encoded by determinants carried on mobile genetic elements, such as plasmids, transposons, and integrons, which are then responsible for the horizontal transfer of antibiotic resistance genes. 细菌中可移动遗传单位如:质粒、转座子和整合子可以携带编码耐药基因的基因盒。整合子是耐药基因水平转移的主要因子。
Thus, we speculated than the multiple of transposons or its remains located in introns of silkworm GST genes could result in more and larger introns. 3. 因此,我们推测这可能是由于家蚕基因组中存在大量的转座子或其残余等重复序列而使家蚕的GST基因内含子数目增多和长度增加。
Fortunately, the silkworm genome sequence and a new assemble have been recently completed, and this provides us with a good opportunity for studying Tcl/ Mariner transposons of the silkworm at a genome-wide scale. 随着家蚕全基因组数据以及家蚕基因组精细图的公布,为全基因组分析Tc1/Mariner转座子提供了一个很好的机会。
Most extant bacteria and some ancient bacterial populations encode ( d) a conjugative system. There are several conjugative transfer units, including self-transmissible plasmids, mobilizable plasmids, transposons, and integrated conjugative units. 大多数细菌和一些古细菌类群可以编码接合系统,存在多种接合转移单元,包括自转移接合质粒,诱动质粒,接合转座子以及一体化的接合单元。
Transposons are specific and independent DNA sequences with translocation features in genome. 转座子是基因组中一段特异的具有转位特性的独立DNA序列。
Multidrug resistance is frequently linked with DNA elements such as integrons, which can be located on transposons and plasmids but also on the chromosome. They can integrate and disseminate genes encoding resistance to a number of antimicrobial drugs. 多重耐药细菌往往携带诸如整合子等基因元件。整合子位于质粒、转座子和基因组上,它们可以整合并且传播大量的耐药基因。
There are 4 types in these sequences: DNA transposons, LTR retrotransposons, LINE retrotransposons and rolling circles. 查找到的散布重复序列共有4种类型:DNA转座子、LTR反转座子、LINE反转座子和滚环转座子。
Mobile elements or transposons are genetic elements that can move, and sometimes spread, within their host genomes. 转座子是基因组内可移动、可扩张的遗传元件。
But now it is clear that transposons can cause some beneficial changes to adaptation and biological survival. 但是现在越来越清楚地知道转座子能导致一些对适应性和生物存活有利的变化。
Compared with other superfamilies of DNA transposons in the silkworm, Tcl/ Mariner elements are almost 90% of the whole DNA transposons. 然而在DNA转座子中,与其它的超家族相比,Tc1/Mariner转座子几乎占到了整个DNA转座子的90%。
The results showed that every base in ITR sequences was important for the activity of transposons. Deletion of any base could result in failture of identification and cut of the transposons. 研究结果表明,IFP2的末端反向重复序列上每一个位点的碱基都对转座子活性有重要的影响,任何一个位点碱基的缺失都会导致转座子不能进行识别和剪切。
Many of the currently known resistance genes are located on mobile genetic elements such as plasmids, transposons, integrons and genomic islands. 已知的许多耐药基因大多位于可移动元件如质粒、转座子、整合子和基因岛上。
Among them, LINE retrotransposons is the most frequent, followed by LTR retrotransposons, DNA transposons and rolling circles. 其中LINE反转座子的数目最多,其次是LTR反转座子,DNA转座子和滚环转座子。