2,3,6,3 ′, 4 ′-Penta-O-acetylsucrose ( 6-PAS) was synthesized from sucrose via tritylation, acetylation, detritylation and acetyl migration. 以蔗糖为原料通过羟基的选择性保护、脱保护及迁移合成了三氯蔗糖的中间体2,3,6,3′,4′-五氧乙酰基蔗糖(6-PAS)。
Reaction of sucrose with trialkyl orthoacetate, subsequent tritylation, acetylation, and detritylation afforded derivatives of sucrose acetate by selectively blocking specific hydroxyls in sucrose and 4-6 acetyl migration. 蔗糖和原乙酸三烷基酯反应后,经三苯甲基化、乙酰化以及乙酰基由4-位到6-位的基团迁移反应,选择性地保护了蔗糖分子中的羟基基团,合成了一系列蔗糖乙酸酯。