Active focal adhesion kinase regulates cell adhesion, migration, proliferation and differentiation by interacting with Src family kinase, phosphatidylinositol 3 kinase, cytoskeletal proteins, Graf and adoptor proteins through the phosphorylated tyrosines and the proline rich sequences. 通过磷酸化酪氨酸位点和富脯氨酸序列,活化的焦点粘着激酶与细胞骨架蛋白、Src族激酶、磷酸肌醇3激酶、Graf以及多种衔接子蛋白相互作用,调节细胞的粘附、迁移、增殖和分化。
Study and Application of Polarographic Absorptive Wave of Nickel(ⅱ)-Tyrosines Complex 镍(Ⅱ)&酪氨酸配合物的极谱研究与应用
Mutation of tyrosines in the cytoplasmic domain of CD3 ε blocks the apoptotic signaling pathway of T lymphocytes CD3ε胞浆区Tyr突变阻断下游的细胞凋亡信号传递
Effects of nitration on phosphorylation of protein tyrosines 蛋白质中酪氨酸硝基化对磷酸化的影响